Proficient Procedure for Preparation of Quinoline Derivatives Catalyzed by NbCl5 in Glycerol as Green Solvent
Synthesis of quinolones by the NbCl5-catalyzed in glycerolea.
aReaction conditions: carbonyl compounds (1.0 mmol), 2-amino-5-chlorobenzophenone or 2-amino benzophenone (1 mmol), NbCl5 (0.1 mmol), and glycerol (2 mL); reactions conducted at 110°C. |
bThe yield refers to pure isolated product.