Saccharomyces cerevisiae Catalyzed Cyclocondensation Reaction: Synthesis of Pyrazoline

Table 2

Effect of amount of catalyst on the synthesis of pyrazoline.

Entry	Catalyst (g)	Time (h)	Yield (%)
1	—	32	00
2	0.5	32	00
3	1	32	30
4	2	32	89
5	3	32	90
6	4	32	90

Reaction condition: chalcone (5 mmol), hydrazine hydrate (10 mmol), and baker’s yeast in methanol (15 mL) at room temperature. Isolated yield.