Research Article

Sedation and Regional Anesthesia for Deep Brain Stimulation in Parkinson’s Disease

Table 2

Hemodynamic, respiratory variables and sedation levels during specific procedures.

HR (beat min−1)MAP (mmHg)BISSpO2 (%)RR (rate min−1)

Baseline81.13 102.36 96.15 (3.07)96.40 (2.68)14.32 (1.06)
Initial sedation 73.47 (11.42)90.52 (15.05)69.80 (5.13)97.21 (2.08)13.13 (0.5)
Stereotactic frame 76.30 (8.28)87.04 (14.51)71.92 (5.36)97.54 (1.53)13.83 (1.27)
CT imaging 75.00 (9.29)86.04 (11.55)87.76 (8.76)98.21 (1.56)13.13 (0.53)
Skin incision 74.54 (8.00)87.59 (12.37)87.76 (8.76)98.47 (1.69)13.13 (0.53)
MER (one side)67.39 (9.27)81.30 (12.62)76.5 (10.09)96.86 (5.19)13.00 (0.78)
Macrostimulation (one side)68.04 (7.49)81.91 (10.05)85.90 (6.11)98.34 (1.84)12.46 (0.93)
MER (other side)63.26 (8.99)76.82 (12.51)80.27 (9.34)98.95 (1.33)13.13 (0.53)
Macrostimulation (other side)65.21 (11.22)77.21 (13.27)87.27 (5.72)98.86 (1.51)13.58 (1.06)
Closure 68.69 (8.55)79.00 (9.96)85.60 (9.37)98.78 (1.50)13.13 (0.53)
PACU 68.04 (7.49)81.91 (10.05)85.90 (6.11)98.34 (1.84)12.46 (0.93)

HR: heart rate, MAP: mean arterial pressure, BIS: bispectral index, SpO2: peripheral oxygen saturation, RR: respiratory rate, CT: computerized tomography, MER: microelectrode recordings, and PACU: post anesthesia care unit. Values are mean (SD), significant difference between baseline HR, MAP and all other measurements.