Table of Contents
Journal of Anthropology
Volume 2012 (2012), Article ID 984180, 5 pages
http://dx.doi.org/10.1155/2012/984180
Research Article

Epidemiological Study of Glucose-6-phosphate Dehydrogenase Deficiency in Scheduled Caste Population of India

Human Molecular Genetics Laboratory, Department of Biotechnology, VBS Purvanchal University, Jaunpur 22001, India

Received 26 November 2011; Revised 23 February 2012; Accepted 29 February 2012

Academic Editor: Santos Alonso

Copyright © 2012 Vandana Rai and Pradeep Kumar. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. F. Kletzien, P. K. W. Harris, and L. A. Foellmi, “Glucose-6-phosphate dehydrogenase: a ‘housekeeping’ enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stress,” The FASEB Journal, vol. 8, no. 2, pp. 174–181, 1994. View at Google Scholar · View at Scopus
  2. L. Luzzatto, A. Mehta, and T. Vulliamy, “Glucose 6-phosphate dehydrogenase deficiency,” in The Metabolic and Molecular Bases of Inherited Disease, C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, Eds., vol. 3, pp. 4517–4533, McGraw-Hill, New York, NY, USA, 8th edition, 2001. View at Google Scholar
  3. L. Luzzatto and G. Battistuzzi, “Glucose-6-phosphate dehydrogenase.,” Advances in Human Genetics, vol. 14, pp. 217–386, 1985. View at Google Scholar · View at Scopus
  4. R. Notaro, A. Afolayan, and L. Luzzatto, “Human mutations in glucose 6-phosphate dehydrogenase reflect evolutionary history,” The FASEB Journal, vol. 14, no. 3, pp. 485–494, 2000. View at Google Scholar · View at Scopus
  5. T. Vulliamy, E. Beutler, and L. Luzzatto, “Variants of glucose-6-phosphate dehydrogenase are due to missense mutations spread throughout the coding region of the gene,” Human Mutation, vol. 2, no. 3, pp. 159–167, 1993. View at Google Scholar · View at Scopus
  6. E. Beutler, “The hemolytic effect of primaquine and related compounds: a review,” Blood, vol. 14, no. 2, pp. 103–139, 1959. View at Google Scholar
  7. Z. Spolarics, M. Siddiqi, J. H. Siegel et al., “Increased incidence of sepsis and altered monocyte functions in severely injured type A- glucose-6-phosphate dehydrogenase-deficient African American trauma patients,” Critical Care Medicine, vol. 29, no. 4, pp. 728–736, 2001. View at Google Scholar · View at Scopus
  8. E. Y. Chen, A. Cheng, A. Lee et al., “Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome,” Genomics, vol. 10, no. 3, pp. 792–800, 1991. View at Publisher · View at Google Scholar · View at Scopus
  9. P. Cohen and M. A. Rosemeyer, “Human glucose-6-phosphate dehydrogenase: purification of the erythrocyte enzyme and the influence of ions on its activity,” European Journal of Biochemistry, vol. 8, no. 1, pp. 1–7, 1969. View at Google Scholar
  10. S. A. Tishkoff, R. Varkonyi, N. Cahinhinan et al., “Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance,” Science, vol. 293, no. 5529, pp. 455–462, 2001. View at Publisher · View at Google Scholar · View at Scopus
  11. E. F. Roth, C. Raventos-Suarez, A. Rinaldi, and R. L. Nagel, “Glucose-6-phosphate dehydrogenase deficiency inhibits in vitro growth of Plasmodium falciparum.,” Proceedings of the National Academy of Sciences of the United States of America, vol. 80, no. 1, pp. 298–299, 1983. View at Google Scholar · View at Scopus
  12. E. A. Usanga and L. Luzzatto, “Adaptation of Plasmodium falciparum to glucose 6-phosphate dehydrogenase-deficient host red cells by production of parasite-encoded enzyme,” Nature, vol. 313, no. 6005, pp. 793–795, 1985. View at Google Scholar · View at Scopus
  13. A. J. Baxi, V. Balakrishnan, J. V. Undevia, and L. D. Sanghvi, “Glucose-6-phosphate dehydrogenase deficiency in the Parsee community, Bombay.,” Indian journal of medical sciences, vol. 17, pp. 493–500, 1963. View at Google Scholar · View at Scopus
  14. S. N. Naik, “Glucose-6-phosphate dehydrogenase deficiency in India and its clinical significance.,” The Journal of the Association of Physicians of India, vol. 42, no. 3, pp. 229–234, 1994. View at Google Scholar · View at Scopus
  15. V. Tripathy and B. Reddy, “Present status of understanding on the G6PD deficiency and natural selection,” Journal of Postgraduate Medicine, vol. 53, no. 3, pp. 193–202, 2007. View at Google Scholar · View at Scopus
  16. R. Samatani, P. R. Mondal, and K. N. Saraswathy, “Glucose-6-phosphate dehydrogenase deficiency and sickle cell hemoglobin among the Warli tribe of Dadra and Nagar Haveli,” The Anthropologist, vol. 10, no. 4, pp. 301–303, 2008. View at Google Scholar · View at Scopus
  17. M. Asghar and M. P. Sachdeva, “Glucose-6-phosphate dehydrogenase deficiency and sickle cell hemoglobin among the Dhodias of Dadra Nagar Haveli,” The Anthropologist, vol. 11, no. 1, pp. 61–62, 2009. View at Google Scholar · View at Scopus
  18. N. A. Devi and M. P. Sachdeva, “Sickle cell haemoglobin and glucose-6- phosphate dehydrogenase deficiency among the rajputs of dadra and nagar haveli,” The Anthropologist, vol. 11, no. 1, pp. 45–47, 2009. View at Google Scholar · View at Scopus
  19. G. J. Brewer, A. R. Tarlov, and A. S. Alving, “The methemoglobin reduction test for primaquine-type sensitivity of erythrocytes. A simplified procedure for detecting a specific hypersusceptibility to drug hemolysis.,” The Journal of the American Medical Association, vol. 180, pp. 386–388, 1962. View at Google Scholar · View at Scopus
  20. N. Achoubi, M. Asghar, S. Y. Meitei, M. P. Sachdeva, K. N. Sarawathy, and B. Murry, “Haemoglobinopathies and glucose-6-phosphate dehydrogenase deficiency in a malaria endemic region of Manipur, northeast India,” Anthropological Science, vol. 118, no. 3, pp. 201–204, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. P. K. Sidhu, K. Kaur, I. Kumar, and S. Lata, “Glucose-6-phosphate dehydrogenase deficiency in blood donors: screening by micromethaemoglobin reduction test,” Indian Journal of Pathology and Microbiology, vol. 44, no. 1, pp. 23–25, 2001. View at Google Scholar · View at Scopus
  22. A. Santhi and M. P. Sachdeva, “Glucose-6-phosphate dehydrogenase deficiency among the jats and brahmins of sampla (Haryana),” The Anthropologist, vol. 6, no. 4, pp. 291–292, 2004. View at Google Scholar
  23. K. N. Saraswathy and S. Aggarwal, “Study of glucose-6- phosphate dehydrogenase deficiency and sickle cell anemia among the Tamil Brahmins of Delhi,” The Anthropologist, vol. 7, no. 1, pp. 45–47, 2005. View at Google Scholar
  24. S. C. Gupte, A. N. Shaw, and K. C. Shah, “Hematological findings and severity of G6PD deficiency in Vataliya Prajapati subjects,” Journal of Association of Physicians of India, vol. 53, pp. 1027–1030, 2005. View at Google Scholar · View at Scopus
  25. P. K. Seth and S. Seth, “Biogenetical studies of Nagas: glucose-6-phosphate dehydrogenase deficiency in Angami Nagas.,” Human Biology, vol. 43, no. 4, pp. 557–561, 1971. View at Google Scholar · View at Scopus
  26. R. S. Balgir, “Genetic burden of red cell enzyme glucose-6-phosphate dehydrogenase deficiency in two major Scheduled Tribes of Sundargarh district, Northwestern Orissa, India,” Current Science, vol. 92, no. 6, pp. 768–774, 2007. View at Google Scholar · View at Scopus
  27. T. P. Sharma and Rajkumari, “Glucose-6-phosphate dehydrogenase deficiency in Danguria Tharu settled in Baharaich district of Uttar Pradesh,” The Anthropologist, vol. 12, no. 1, pp. 59–61, 2010. View at Google Scholar · View at Scopus
  28. M. K. Bhasin and H. Walter, Genetic of Caste and Tribes of India, Kamla-Raj Enterprises, Delhi, India, 2001.
  29. M. K. Bhasin, “Genetics of castes and tribes of India: glucose- 6-phosphate dehydrogenase deficiency and abnormal haemoglobins (HbS and HbE),” International Journal of Human Genetics, vol. 6, no. 1, pp. 49–72, 2006. View at Google Scholar
  30. D. P. Steensma, J. D. Hoyer, and V. F. Fairbanks, “Hereditary red blood cell disorders in Middle Eastern patients,” Mayo Clinic Proceedings, vol. 76, no. 3, pp. 285–293, 2001. View at Google Scholar · View at Scopus
  31. P. Verlé, D. H. Nhan, T. T. Tinh et al., “Glucose-6-phosphate dehydrogenase deficiency in northern Vietnam,” Tropical Medicine and International Health, vol. 5, no. 3, pp. 203–206, 2000. View at Publisher · View at Google Scholar · View at Scopus
  32. A. S. Gandapur, F. Qureshi, G. Mustafa, S. Baksh, M. Ramzan, and M. A. Khan, “Frequency of glucose 6 phosphate dehydrogenase deficiency and related hemolytic anemia in Riyadh, Saudi Arabia.,” Journal of Ayub Medical College, vol. 14, no. 3, pp. 24–26, 2002. View at Google Scholar · View at Scopus
  33. J. May, C. G. Meyer, L. Großterlinden et al., “Red cell glucose-6-phosphate dehydrogenase status and pyruvate kinase activity in a Nigerian population,” Tropical Medicine and International Health, vol. 5, no. 2, pp. 119–123, 2000. View at Publisher · View at Google Scholar · View at Scopus
  34. J. C. Bouanga, R. Mouélé, C. Préhu, H. Wajcman, J. Feingold, and F. Galactéros, “Glucose-6-phosphate dehydrogenase deficiency and homozygous sickle cell disease in Congo,” Human Heredity, vol. 48, no. 4, pp. 192–197, 1998. View at Publisher · View at Google Scholar · View at Scopus
  35. B. Duflo, A. Diallo, K. Toure, and G. Soula, “Glucose-6-phosphate dehydrogenase deficiency in Mali. Epidemiology and pathological role,” Bulletin de la Societe de Pathologie Exotique et de ses Filiales, vol. 72, no. 3, pp. 258–264, 1979. View at Google Scholar · View at Scopus
  36. J. C. Davis, T. D. Clark, S. K. Kemble et al., “Longitudinal study of urban malaria in a cohort of Ugandan children: description of study site, census and recruitment,” Malaria Journal, vol. 5, article no. 18, 2006. View at Publisher · View at Google Scholar · View at Scopus
  37. F. Migot-Nabias, L. E. Mombo, A. J. F. Luty et al., “Human genetic factors related to susceptibility to mild malaria in Gabon,” Genes and Immunity, vol. 1, no. 7, pp. 435–441, 2000. View at Google Scholar · View at Scopus
  38. H. Matsuoka, M. Arai, S. Yoshida et al., “Five different glucose-6-phophate dehydrogenase (G6PD) variants found among 11 G6PD-deficient persons in Flores Island, Indonesia,” Journal of Human Genetics, vol. 48, no. 10, pp. 541–544, 2003. View at Publisher · View at Google Scholar · View at Scopus
  39. I. Nuchprayoon, S. Sanpavat, and S. Nuchprayoon, “Glucose-6-phosphate dehydrogenase (G6PD) mutations in Thailand: G6PD Viangchan (871G>A) is the most common deficiency variant in the Thai population.,” Human mutation, vol. 19, no. 2, p. 185, 2002. View at Google Scholar · View at Scopus
  40. J. Wang, E. Luo, M. Hirai et al., “Nine different glucose-6-phosphate dehydrogenase (G6PD) variants in a Malaysian population with Malay, Chinese, Indian and Orang Asli (Aboriginal Malaysian) backgrounds,” Acta Medica Okayama, vol. 62, no. 5, pp. 327–332, 2008. View at Google Scholar · View at Scopus
  41. H. Y. Ho, M. L. Cheng, S. F. Weng et al., “Glucose-6-phosphate dehydrogenase deficiency enhances enterovirus 71 infection,” Journal of General Virology, vol. 89, no. 9, pp. 2080–2089, 2008. View at Publisher · View at Google Scholar · View at Scopus
  42. N. Akhter, N. Begum, and W. A. Khan, “Glucose-6-phosphate dehydrogenase (G6PD) status in neonatal jaundice and its relationship with severity of hyperbilirubinemia,” Journal of Bangladesh Society of Physiologist, vol. 4, no. 2, pp. 71–76, 2009. View at Google Scholar
  43. N. Ali, M. Anwar, M. Ayyub, F. A. Bhatti, M. Nadeem, and A. Nadeem, “Frequency of glucose-6-phosphate dehydrogenase deficiency in some ethnic groups of Pakistan,” Journal of the College of Physicians and Surgeons Pakistan, vol. 15, no. 3, pp. 137–141, 2005. View at Google Scholar · View at Scopus
  44. B. Moiz, A. Nasir, T. Moatter, Z. Ali Naqvi, and M. Khurshid, “Population study of 1311 C/T polymorphism of Glucose 6 Phosphate Dehydrogenase gene in Pakistan—an analysis of 715 X-chromosomes,” BMC Genetics, vol. 10, article no. 41, 2009. View at Publisher · View at Google Scholar · View at Scopus
  45. C. S. Huang, K. L. Hung, M. J. Huang, Y. C. Li, T. H. Liu, and T. K. Tang, “Neonatal jaundice and molecular mutations in glucose-6-phosphate dehydrogenase deficient newborn infants,” American Journal of Hematology, vol. 51, no. 1, pp. 19–25, 1996. View at Google Scholar
  46. I. Nuchprayoon, C. Louicharoen, and W. Charoenvej, “Glucose-6-phosphate dehydrogenase mutations in Mon and Burmese of southern Myanmar,” Journal of Human Genetics, vol. 53, no. 1, pp. 48–54, 2008. View at Publisher · View at Google Scholar · View at Scopus
  47. K. Iwai, A. Hirono, H. Matsuoka et al., “Distribution of glucose-6-phosphate dehydrogenase mutations in Southeast Asia,” Human Genetics, vol. 108, no. 6, pp. 445–449, 2001. View at Publisher · View at Google Scholar · View at Scopus
  48. L. Luzzatto and A. Mehta, “Glucose-6-phos-phate dehydrogenase deficiency,” in The Metabolic of Inherited Disease, C. R. Scriver, A. L. Baudet, W. S. Sly, and D Valle, Eds., pp. 2237–2265, McGraw-Hill, New York, NY, USA, 6th edition, 1989. View at Google Scholar
  49. E. Beutler, “The genetics of glucose-6-phosphate dehydrogenase deficiency,” Seminars in Hematology, vol. 27, no. 2, pp. 137–164, 1990. View at Google Scholar · View at Scopus
  50. F. A. Hilmi, N. A. Al-Allwi, M. Rassam, G. Al-Shamma, and A. Al-Hashimi, “Red cell glucose-6-phosphate dehydrogenase phenotypes in Iraq,” Eastern Mediterranean Health Journal, vol. 8, no. 1, pp. 42–48, 2002. View at Google Scholar · View at Scopus
  51. E. A. Usanga and R. Ameen, “Glucose-6-phosphate dehydrogenase deficiency in Kuwait, Syria, Egypt, Iran, Jordan and Lebanon,” Human Heredity, vol. 50, no. 3, pp. 158–161, 2000. View at Google Scholar · View at Scopus
  52. A. Al-Riyami and G. J. Ebrahim, “Genetic blood disorders survey in the Sultanate of Oman,” Journal of Tropical Pediatrics, vol. 49, supplement 1, pp. i1–i20, 2003. View at Google Scholar · View at Scopus
  53. R. A. Bayoumi, M. S. A. Nur-E-Kamal, M. Tadayyon et al., “Molecular characterization of erythrocyte glucose-6-phosphate dehydrogenase deficiency in Al-Ain District, United Arab Emirates,” Human Heredity, vol. 46, no. 3, pp. 136–141, 1996. View at Google Scholar · View at Scopus
  54. L. Hussein, G. Yamamah, and A. Saleh, “Glucose-6-phosphate dehydrogenase deficiency and sulfadimidin acetylation phenotypes in Egyptian oases,” Biochemical Genetics, vol. 30, no. 3-4, pp. 113–121, 1992. View at Publisher · View at Google Scholar · View at Scopus
  55. S. Al Arrayed, “Campaign to control genetic blood diseases in Bahrain,” Community Genetics, vol. 8, no. 1, pp. 52–55, 2005. View at Publisher · View at Google Scholar · View at Scopus
  56. C. Altay and F. Gumruk, “Red cell glucose-6-phosphate dehydrogenase deficiency in Turkey,” Turkish Journal of Hematology, vol. 25, no. 1, pp. 1–7, 2008. View at Google Scholar · View at Scopus
  57. M. D. Segeja, B. P. Mmbando, M. L. Kamugisha et al., “Prevalence of glucose-6-phosphate dehydrogenase deficiency and haemoglobin S in high and moderate malaria transmission areas of Muheza, north-eastern Tanzania.,” Tanzania Journal of Health Research, vol. 10, no. 1, pp. 9–13, 2008. View at Google Scholar · View at Scopus
  58. J. M. White, M. Byrne, R. Richards, T. Buchanan, E. Katsoulis, and K. Weerasingh, “Red cell genetic abnormalities in Peninsular Arabs: sickle haemoglobin, G6PD deficiency, and alpha and beta thalassaemia,” Journal of Medical Geneics, vol. 23, no. 3, pp. 245–251, 1986. View at Google Scholar
  59. M. K. Alabdulaali, K. M. Alayed, A. F. Alshaikh, and S. A. Almashhadani, “Prevalence of glucose-6-phosphate dehydrogenase deficiency and sickle cell trait among blood donors in Riyadh,” Asian Journal of Transfusion Science, vol. 4, no. 1, pp. 31–33, 2010. View at Google Scholar
  60. H. Matsuoka, D. T. V. Thuan, H. Van Thien et al., “Seven different glucose-6-phosphate dehydrogenase variants including a new variant distributed in Lam Dong Province in southern Vietnam,” Acta Medica Okayama, vol. 61, no. 4, pp. 213–219, 2007. View at Google Scholar · View at Scopus
  61. H. Matsuoka, C. Nguon, T. Kanbe et al., “Glucose-6-phosphate dehydrogenase (G6PD) mutations in Cambodia: G6PD Viangchan (871G>A) is the most common variant in the Cambodian population,” Journal of Human Genetics, vol. 50, no. 9, pp. 468–472, 2005. View at Publisher · View at Google Scholar · View at Scopus
  62. T. K. Chan and D. Todd, “Characteristics and distribution of glucose-6-phosphate dehydrogenase-deficient variants in South China.,” American Journal of Human Genetics, vol. 24, no. 4, pp. 475–484, 1972. View at Google Scholar · View at Scopus