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Journal of Botany
Volume 2012 (2012), Article ID 685427, 6 pages
http://dx.doi.org/10.1155/2012/685427
Research Article

Phytochemical Composition and Antioxidant Potential of Ruta graveolens L. In Vitro Culture Lines

Department of Botany, University of Pune, Pune Maharashtra 411007, India

Received 20 July 2011; Accepted 14 January 2012

Academic Editor: Gaoming Jiang

Copyright © 2012 Renuka Diwan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. C. Cook and S. Samman, “Flavonoids—Chemistry, metabolism, cardioprotective effects, and dietary sources,” Journal of Nutritional Biochemistry, vol. 7, no. 2, pp. 66–76, 1996. View at Publisher · View at Google Scholar · View at Scopus
  2. J. T. Kumpulainen and J. T. Salonen, Natural Antioxidants and Anticarcinogens in Nutrition, Health and Disease, Royal Society of Chemistry, Cambridge, UK, 1999.
  3. K. C. Preethi, C. K. K. Nair, and R. Kuttan, “Clastogenic potential of Ruta graveolens extract and a homeopathic preparation in mouse bone marrow cells,” Asian Pacific Journal of Cancer Prevention, vol. 9, no. 4, pp. 763–769, 2008. View at Google Scholar · View at Scopus
  4. S. Pathak, A. Multani, P. Banerji, and P. Banerji, “Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: a novel treatment for human brain cancer,” International Journal of Oncology, vol. 23, no. 4, pp. 975–982, 2003. View at Google Scholar · View at Scopus
  5. K. Preethi, G. Kuttan, and R. Kuttan, “Anti-tumour activity of Ruta graveolens extract,” Asian Pacific Journal of Cancer Prevention, vol. 7, no. 3, pp. 439–443, 2006. View at Google Scholar · View at Scopus
  6. G. Miliauskas, P. R. Venskutonis, and T. A. van Beek, “Screening of radical scavenging activity of some medicinal and aromatic plant extracts,” Food Chemistry, vol. 85, no. 2, pp. 231–237, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. X. Liu, M. Zhao, J. Wang, B. Yang, and Y. Jiang, “Antioxidant activity of methanolic extract of emblica fruit (Phyllanthus emblica L.) from six regions in China,” Journal of Food Composition and Analysis, vol. 21, no. 3, pp. 219–228, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Gulluce, M. Sokmen, D. Daferera et al., “In vitro antibacterial, antifungal, and antioxidant activities of the essential oil and methanol extracts of herbal parts and callus cultures of Satureja hortensis L,” Journal of Agricultural and Food Chemistry, vol. 51, no. 14, pp. 3958–3965, 2003. View at Publisher · View at Google Scholar
  9. E. N. Frankel and A. S. Meyer, “The problems of using one-dimensional methods to evaluate multifunctional food and biological antioxidants,” Journal of the Science of Food and Agriculture, vol. 80, no. 13, pp. 1925–1941, 2000. View at Publisher · View at Google Scholar · View at Scopus
  10. R. Diwan and N. Malpathak, “Histochemical localization in Ruta graveolens cell cultures: elucidating the relationship between cellular differentiation and furanocoumarin production,” In Vitro Cellular and Developmental Biology, vol. 46, no. 1, pp. 108–116, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. R. Diwan and N. Malpathak, “Novel technique for scaling up of micropropagated Ruta graveolens shoots using liquid culture systems: a step towards commercialization,” New Biotechnology, vol. 25, no. 1, pp. 85–91, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. V. Singleton, R. Orthofer, and R. Lamuela-Raventos, “Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent,” in Methods in Enzymology, L. Packer, Ed., vol. 299, pp. 152–315, Academic Press, San Diego, Calif, USA, 1999. View at Google Scholar
  13. M. R. Szabo, C. Idiţoiu, D. Chambre, and A. X. Lupea, “Improved DPPH determination for antioxidant activity spectrophotometric assay,” Chemical Papers, vol. 61, no. 3, pp. 214–216, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. C. Teow, V. Truong, R. McFeeters, R. Thompson, K. Pecota, and C. Yencho, “Antioxidant activities, phenolic and β-carotene contents of sweet potato genotypes with varying flesh colours,” Food Chemistry, vol. 103, no. 3, pp. 829–838, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. P. Prieto, M. Pineda, and M. Aguilar, “Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E,” Analytical Biochemistry, vol. 269, no. 2, pp. 337–341, 1999. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Oyaizu, “Studies on products of the browning reaction. Antioxidative activities of browning reaction products prepared from glucosamine,” Japanese Journal of Nutrition, vol. 44, no. 6, pp. 307–315, 1986. View at Google Scholar
  17. L. Marcocci, J. Maguire, M. Droy-Lefaix, and L. Packer, “The nitric oxide-scavenging properties of Ginkgo biloba extract EGb 761,” Biochemical and Biophysical Research Communications, vol. 201, no. 2, pp. 748–755, 1994. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Karagozler, B. Erdag, Y. Emek, and D. Uygun, “Antioxidant activity and proline content of leaf extracts from Dorystoechas hastate,” Food Chemistry, vol. 111, pp. 400–447, 2008. View at Google Scholar
  19. X. Piao, I. Park, S. Baek, H. Kim, M. Park, and J. Park, “Antioxidative activity of furanocoumarins isolated from Angelicae dahuricae,” Journal of Ethnopharmacology, vol. 93, no. 2, pp. 243–246, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. I. Grzegorczyk, A. Matkowski, and H. Wysokinska, “Antioxidant activity of extracts from in vitro cultures of Salvia officinalis L,” Food Chemistry, vol. 104, no. 2, pp. 536–541, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. F. Borges, F. Roleira, N. Milhazes, L. Santana, and E. Uriarte, “Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity,” Current Medicinal Chemistry, vol. 12, no. 8, pp. 887–916, 2005. View at Publisher · View at Google Scholar · View at Scopus
  22. I. Kostova, “Synthetic and natural coumarins as cytotoxic agents,” Current Medicinal Chemistry, vol. 5, no. 1, pp. 29–46, 2005. View at Publisher · View at Google Scholar · View at Scopus
  23. R. Marwah, M. Fatope, R. Al Mahrooqi, G. B. Varma, H. Al Abadi, and S. Al-Burtamani, “Antioxidant capacity of some edible and wound healing plants in Oman,” Food Chemistry, vol. 101, no. 2, pp. 465–470, 2007. View at Publisher · View at Google Scholar · View at Scopus