Immunohistochemical Characterization of Three Monoclonal Antibodies Raised against the Epidermal Growth Factor and Its Receptor in Non-Small-Cell Lung Cancer: Their Potential Use in the Selection of Patients for Immunotherapy
Figure 3
Hematoxylin and eosin staining of squamous cell carcinoma of the lung (a). Note: the intense reaction of ior egf/r3 Mab is mainly located in cell membrane and also in the cytoplasm of malignant epithelial cells (b) (inset on the upper-right corner, 1000x magnification). An intense immunostaining with both CB-EGF1 and CB-EGF2 Mabs was also evidenced (c and d, resp.). Black bar =100 μm.
