Research Article

Immunohistochemical Characterization of Three Monoclonal Antibodies Raised against the Epidermal Growth Factor and Its Receptor in Non-Small-Cell Lung Cancer: Their Potential Use in the Selection of Patients for Immunotherapy

Table 2

Tumor characteristic.

FeaturesNo. (%)

Histopathological type
Small cell lung carcinoma12/71 (16.90)
Non-small cell lung carcinoma
 Squamous cell carcinoma20/71 (28.17)
 Adenocarcinoma23/71 (32.39)
 Large cell carcinoma6/71 (8.45)
 Other 10/71 (14.08)
Grade of differentiation
 Well 10/71 (14.08)
 Moderate24/71 (33.80)
 Poor22/71 (30.99)
 Undifferentiated15/71 (21.13)
Degree of cell pleomorphism
 No evident3/71 (4.22)
 Low29/71 (40.85)
 Moderate23/71 (32.39)
 High16/71 (22.53)
Necrosis index
 No evident27/71 (38.03)
17/71 (23.94)
27/71 (38.03)
Mitotic index
 No evident8/71 (11.27)
 Low22/71 (30.99)
 Moderate22/71 (30.99)
 High19/71 (26.76)

No.: number of cases; %: percentages.