Journal of Biomarkers / 2013 / Article / Tab 1

Research Article

Association between a Tetranucleotide Repeat Polymorphism of SPAG16 Gene and Cataract in Male Children

Table 1

Allele and genotype frequencies of D2S2944 microsatellite repeat in pediatric cataract cases and controls.

PCR Pdt
Size (bp)
(GATA) repeatsAlleleCases
Control

Allele frequency, 2 (%)

1000810 (00)0 (00)
1040920 (00)4 (02)
1081038 (03)12 (05)
11211419 (10)a42 (19)a
11612548 (25)69 (31)
12013650 (26)b 32 (15)b
12414756 (29)46 (21)
12815813 (07)15 (07)
1321690 (00)00 (00)

Genotype frequency, (%)

<120<13626 (27)48 (44)
<120/≥120<13/≥13<6/≥624 (25)31 (28)
≥120≥13≥647 (48)31 (28)

Allele and genotype distribution in cases versus controls, respectively: (trend) = 10.981, , ; (trend) = 9.669, , . aOR = 0.45, CI95% = 0.25–0.81, , ; bOR = 2.01, CI95% = 1.23–3.33, , . Note—<13 includes all homozygotes with both alleles less than 120 bp PCR pdt length, while <13/>13 includes heterozygotes with at least one 120 bp PCR pdt length allele and ≥13: homozygotes with both alleles more than 120 bp PCR pdt length. Pdt = product.

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