Effect of Quercetin on Haematobiochemical and Histological Changes in the Liver of Polychlorined Biphenyls-Induced Adult Male Wistar Rats
Figure 4
Liver histology in control, quercetin-, PCB, and PCB+Quercetin-treated adult male rats (Haematoxylin and Eosin staining, ((a), (b), (c), (d) 40x) and ((e), (f), (g), (h) 100x). Photomicrograph of the liver cells ((e)-(f)) Liver sections of control (e) and quer-treated (f) rats showing normal histological appearance of the liver, including portal canal (PC), hepatocytes (H), centrally located nuclei (N), and Kupffer cell (K). (g) Section of rat liver treated with PCB revealed considerable number of damaged hepatocytes (H) that have lost their characteristic appearance, with appearance of Pyknotic Nuclei (PN), apoptotic hepatocytes (bolded arrow) and dilation in blood sinusoids (DBS). (h) Liver section of the rat treated with PCB supplemented with quer demonstrated restoration of normal arrangement of hepatocytes, although few damaged hapatoctes were also observed. (Haemotoxylin and Eosin staining, 40x and 100x).
