A Study on MTHFR C677T Gene Polymorphism and Alcohol Dependence among Meiteis of Manipur, India

Table 3

Relative risk analysis (Odds Ratio) of MTHFR C677T polymorphism and different drinking patterns.

MTHFR C677T	AD	Control	ND	OD	MD	OR^1 (95% CI)		OR^2 (95% CI)		OR^3 (95% CI)		OR^4 (95% CI)
CC	91	228	89	81	58	Reference		Reference		Reference		Reference
CT	44	78	29	28	21	1.41 (0.91–2.20)	0.12	1.48 (0.85–2.58)	0.16	1.06 (0.58–1.93)	0.84	1.11 (0.58–2.13)	0.75
TT	4	7	3	4	0	1.43 (0.41–5.01)	—	1.30 (0.28–5.99)	—	1.46 (0.32–6.74)	—	—	—
CT + TT	48	85	32	32	21	1.41 (0.92–2.17)	0.11	1.47 (0.86–2.50)	0.16	1.10 (0.62–1.95)	0.75	1.01 (0.53–1.91)	1

ND: nondrinkers; OD: occasional drinkers; MD: moderate drinkers.
OR¹: odd ration between AD and control; OR²: odd ration between AD and ND; OR³: odd ration between ND and OD; OR⁴: odd ration between ND and MD; CI: confidential interval.
= AD versus control (ND + OD + MD); = AD versus ND; = ND versus OD; = ND versus MD; significance level at 5%.