Urinary β2-Microglobulin Is a Good Indicator of Proximal Tubule Injury: A Correlative Study with Renal Biopsies

Figure 1

(a) Normal proximal tubules with back to back proximal tubules and abundant cytoplasm (H&E 40 × 10). (b) In addition to flattening and simplification of tubular epithelium, injured proximal tubules show granular cytoplasmic and membrane staining for KIM-1 (20 × 10). (c) Ischemia type of tubular injury shows flattening and simplification of tubular epithelium (H&E 40 × 10). (d) In addition to flattened tubular epithelium, toxic type of tubular injury reveals vacuoles in cytoplasm (H&E 40 × 10).

(a)

(b)

(c)

(d)