Diagnosis of Non-ST-Elevation Acute Coronary Syndrome by the Measurement of Heart-Type Fatty Acid Binding Protein in Serum: A Prospective Case Control Study

Table 4

Estimated specificity for a range of fixed and prespecified sensitivities and vice versa for cardiac biomarkers.

Variable	cTnI
Estimated specificity at fixed sensitivity
Sensitivity	Specificity	95% CI	Criterion (𝜇g/L)
80.00	59.09	31.82 to 72.73	>0.008
90.00	59.09	31.82 to 72.73	>0.008
95.00	59.09	31.82 to 72.73	>0.008
97.50	59.09	31.82 to 72.73	>0.008
Estimated sensitivity at fixed specificity
Specificity	Sensitivity	95% CI	Criterion (𝜇g/L)
80.00	54.67	36.30 to 72.00	>0.0085
90.00	47.33	30.94 to 64.00	>0.0088
95.00	43.67	27.36 to 61.37	>0.0089
97.50	41.83	25.49 to 60.74	>0.0089
Variable	cTnT
Estimated specificity at fixed sensitivity
Sensitivity	Specificity	95% CI	Criterion (𝜇g/L)
80.00	40.91	10.47 to 59.09	>8
90.00	40.91	13.64 to 59.09	>8
95.00	40.91	13.64 to 59.09	>8
97.50	40.91	13.64 to 59.09	>8
Estimated sensitivity at fixed specificity
Specificity	Sensitivity	95% CI	Criterion (𝜇g/L)
80.00	55.69	39.78 to 71.18	>8.6615
90.00	51.18	35.24 to 68.13	>8.8308
95.00	48.92	32.63 to 67.04	>8.9154
97.50	47.79	31.32 to 65.53	>8.9577
Variable	H-FABP
Estimated specificity at fixed sensitivity
Sensitivity	Specificity	95% CI	Criterion (ng/mL)
80.00	45.45	13.64 to 68.18	>3.15
90.00	45.45	20.26 to 77.27	>2.9
95.00	27.27	4.55 to 59.09	>2.3
97.50	9.09	0.00 to 26.18	>1.75
Estimated sensitivity at fixed specificity
Specificity	Sensitivity	95% CI	Criterion (ng/mL)
80.00	60.00	36.67 to 76.67	>5.06
90.00	56.67	30.00 to 70.00	>5.46
95.00	56.67	33.33 to 70.00	>5.68
97.50	56.67	33.33 to 70.00	>6.06