Journal of Biomarkers / 2015 / Article / Tab 1

Research Article

In Search of Biomarkers for Idiopathic Scoliosis: Leptin and BMP4 Functional Polymorphisms

Table 1

Genotype and allele frequency distributions in patients () with idiopathic scoliosis (IS) and healthy controls ().

Gene,
polymorphism
Genotype,
allele
Cases
, %
Controls
, %
value

Leptin
rs7799039
AA25 (27.8)55 (30.6) 0.64
AG42 (46.7)88 (48.9)
GG23 (25.6)37 (20.6)
A92 (51.1)198 (55.0) 0.39
G88 (48.9)162 (45.0)

BMP4
rs4898820
TT27 (30.0)46 (25.6) 0.74
GT46 (51.1)99 (55.0)
GG17 (18.9)35 (19.4)
T100 (55.6)191 (53.1) 0.58
G80 (44.4)169 (46.9)

A -value < 0.05 was considered to be statistically significant. BMP4 indicates bone morphogenetic protein 4.

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