Research Article

The Diagnostic Value of Serum C-Reactive Protein for Identifying Pneumonia in Hospitalized Patients with Acute Respiratory Symptoms

Table 1

Baseline characteristics of patients admitted with lower respiratory tract infections.

Pneumonia
()
Other lower respiratory tract infections
()
value

Demographics
Age, years72 (56–80)79 (71–85)<0.01
Gender, male349 (63)232 (54)0.84
Comorbidity (Charlson index)4 (2–6)6 (4–7)<0.01

Clinical variables
Days of symptoms4 (2–7)4 (2–7)0.27
Previous antibiotic treatment164 (33)100 (30)0.40
Heart rate (bpm)98 (84–110)97 (84–110)0.56
Respiratory rate (rpm)28 (24–32)28 (24–32)0.79
Systolic blood pressure (mmHg)123 (109–140)133 (116–146)<0.01
Diastolic blood pressure (mmHg)69 (60–78)71 (63–82)<0.01
Temperature (°C)
 No fever (<37°C)197 (35)219 (60)<0.01
 Low-grade fever (37-38°C)163 (29)87 (24)
 High-grade fever (>38°C)197 (35)60 (16)

Laboratory findings
Basal pO2(mmHg)61 (55–70)62 (55–72)0.19
C-reactive protein (mg/L)187 (123–278)59 (24–108)<0.01
Leukocyte count (×109/L)13.3 (9.27–17.65)10.8 (7.97–13.30)<0.01
Creatinine (mg/dL)1.0 (0.8–1.3)0.9 (0.7–1.2)0.01

Microbiology findings
Microorganism found169 (30.3%)30 (8.9%)<0.01

Follow-up
Days in hospital6 (4–10)6 (4–9)0.05
Intensive care unit transfers37 (7)4 (1)<0.01
In-hospital mortality31 (6)16 (4)0.45

Quantitative variables are shown as medians (IQR 25–75) and qualitative variables as absolute numbers (percentages). Other lower respiratory tract infections included acute bronchitis and acute exacerbations of COPD.