Association Study between Promoter Polymorphism of TPH1 and Progression of Idiopathic Scoliosis

Table 3

Odds ratios of genotypes and alleles of tryptophan hydroxylase 1 (TPH1) polymorphism rs10488682 (T/A) in the progressive group (with and without bracing).

Progressive group	Genotype, allele	()	value	OR [95% CI]
Previous bracing/without bracing; (, )	TT versus AA	1/4 versus 26/17	0.15	0.16 0.02–1.59]
	TT + TA versus AA	23/17 versus 26/17	0.83	0.88 0.37–2.12]
	TT versus TA + AA	1/4 versus 48/30	0.15	0.16 0.02–1.47]
	T versus A	24/21 versus 74/47	0.38	0.73 0.36–1.45]

A value of was considered to be statistically significant. OR indicates odds ratio; CI, confidence interval; , , number of patients.