Tropomyosin Period 3 Is Essential for Enhancement of Isometric Tension in Thin Filament-Reconstituted Bovine Myocardium
Figure 1
Tropomyosins used for reconstitution. The structure of ācoli-synthesized Tm used for our study, highlighting the 7 quasirepeat regions. The N-terminal amino acid residue for each region is shown underneath nf Yellow color represents the region(s) deleted in the respective mutants. was previously studied [13, 14] and is included here for the sake of comparison. nf is the full-length protein and was used as a control. The N-terminus of has the Ala-Ser substitution, whereas the N-termini of , and nf do not have this substitution.