Table of Contents
Journal of Biophysics
Volume 2013, Article ID 525231, 11 pages
http://dx.doi.org/10.1155/2013/525231
Research Article

Analysis of the REJ Module of Polycystin-1 Using Molecular Modeling and Force-Spectroscopy Techniques

1Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555, USA
2Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA
3Department of Medicine, Division of Nephrology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
4Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA
5Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA

Received 28 November 2012; Accepted 7 May 2013

Academic Editor: P. Bryant Chase

Copyright © 2013 Meixiang Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The Supplementary Material contains far-UV CD spectroscopy of the (I27)3-REJd4-(I27)2 protein construct and a control plot of a steered molecular dynamics simulations of the mechanical unfolding of titin domain I27.

  1. Supplementary Material