Table of Contents
Journal of Blood Transfusion
Volume 2012, Article ID 473514, 3 pages
http://dx.doi.org/10.1155/2012/473514
Clinical Study

Comparative Efficacy of Three Forms of Parenteral Iron

1Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK
2Department of Haematology, Kings College Hospital, London SE5 9RS, UK

Received 18 August 2011; Revised 26 October 2011; Accepted 4 November 2011

Academic Editor: P. M. Kopko

Copyright © 2012 Richard Dillon et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Intravenous iron therapy is a useful treatment for the rapid correction of iron deficiency anaemia and can be used to avoid or reduce the requirement for allogeneic blood transfusion. Several intravenous iron preparations are available commercially which differ in cost, mode of administration and side effect profile. There are few data directly comparing the efficacy of these preparations. In this retrospective single-centre study, we present the results from two hundred and eight patients treated using three different iron preparations (iron dextran, iron sucrose and ferric carboxymaltose) and compare the effect on haemoglobin levels and other measures of iron deficiency six weeks after treatment. Within the limitations of our study design, we show a statistically and clinically significant difference in efficacy between these preparations.