Research Article
QSAR Investigation on Quinolizidinyl Derivatives in Alzheimer’s Disease
Table 5
Experimental and predicted values of log (1/IC50) using PCR and PLS methods.
| Observed log (1/IC50) | Predicted PCR | Predicted PLS |
| 1.531 | 1.534 | 1.426 | 1.653 | 1.656 | 1.656 | 0.854 | 1.340 | 1.327 | 1.591 | 1.679 | 1.675 | 1.771 | 1.713 | 1.893 | 1.568 | 1.647 | 1.661 | 1.699 | 1.657 | 1.660 | 1.74 | 1.482 | 1.401 | 0.919 | 1.429 | 1.351 | 1.634 | 1.572 | 1.489 | 0.845 | 1.684 | 1.677 | 1.623 | 2.260 | 2.324 | 1.763 | 1.630 | 1.625 | 1.663 | 1.423 | 1.341 | 0.919 | 1.282 | 1.203 | 1.613 | 1.560 | 1.602 | 1.653 | 1.574 | 1.614 | 1.681 | 1.574 | 1.614 | 0.949 | 1.047 | 1.080 | 0.826 | 1.042 | 1.073 | 1.544 | 1.068 | 1.100 | 1.653 | 0.919 | 0.956 | 1.653 | 1.767 | 1.701 | 1.69 | 1.693 | 1.726 | 1.477 | 1.689 | 1.722 | 1.505 | 1.358 | 1.370 | 1.672 | 1.212 | 1.275 | 1.602 | 1.467 | 1.503 | 1.672 | 1.160 | 1.153 | 0.833 | 0.962 | 0.919 | 0.756 | 0.733 | 0.630 | 1.532 | 1.161 | 1.076 | 1.623 | 1.579 | 1.584 | 1.462 | 1.193 | 1.171 | 1.69 | 1.491 | 1.387 | 0.863 | 0.521 | 0.581 | −0.076 | 0.275 | 0.276 | −0.658 | 0.022 | −0.026 | 1.756 | 1.010 | 1.062 | 0.82 | 0.417 | 0.497 | −0.456 | 0.431 | 0.495 | 0.079 | 0.273 | 0.337 |
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