513537.fig.003a
(a)
513537.fig.003b
(b)
Figure 3: (a) LASSO models implemented in ChemSpider. (b) LASSO scores for Mibolerone, a strong AR and ER binder found with a LASSO search on ChemSpider. The LASSO score is significant only for 4 targets: MR, AR, ER and PR while the rest of the 40 targets are all 0.10 or below for this molecule.