Table of Contents
Journal of Computational Medicine
Volume 2014, Article ID 653845, 9 pages
Review Article

Modeling Requirements for Computer Simulation of Cerebral Aneurysm

1VFE Research Institute, University of Tehran (Campus 2), College of Engineering, 4th Floor of Institute of Petroleum Engineering Building, North Kargar Avenue, Tehran 14399-56191, Iran
2School of Mechanical Engineering, University of Tehran, Tehran 14399-56191, Iran
3Sina Trauma Research Center, Tehran University of Medical Science, Tehran 14399-56191, Iran

Received 20 November 2013; Revised 8 January 2014; Accepted 8 January 2014; Published 16 February 2014

Academic Editor: Michele Migliore

Copyright © 2014 S. R. Ghodsi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. In order to reduce the mortality risk of aneurysm rupture, a timely diagnosis and treatment are vital. There are different reasons for aneurysm, such as hypertension, arteriosclerosis, and heredity. An efficient and cost-effective method to study the generation, development, and rupture of aneurysm and also analysis of treatment methods can accelerate progress. The Computational Fluid Dynamics is a well-known tool to simulate various phenomena. A reliable virtual modeling in biology depends on our knowledge about variety of characteristics, that is, biological features, structural properties, and flow conditions. Objective. Because of the vast research about the related subjects, an organized review is required. The aim of current review article is classification of the required foundations for a reliable virtual modeling of cerebral aneurysm, especially in the Circle of Willis.