Table of Contents
Journal of Cancer Research
Volume 2013, Article ID 818675, 8 pages
http://dx.doi.org/10.1155/2013/818675
Research Article

Fecal Collection and Stabilization Methods for Improved Fecal DNA Test for Colorectal Cancer in a Screening Setting

ISPO, Cancer Prevention and Research Institute, Analytical and Biomolecular Cytology Unit, Via Cosimo il Vecchio 2, 50139 Florence, Italy

Received 10 April 2013; Revised 24 July 2013; Accepted 11 August 2013

Academic Editor: Mario Scartozzi

Copyright © 2013 Francesca Maria Carozzi and Cristina Sani. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Y. Koga, M. Yasunaga, S. Katayose et al., “Improved recovery of exfoliated colonocytes from feces using newly developed immunomagnetic beads,” Gastroenterology Research and Practice, vol. 2008, Article ID 605273, 7 pages, 2008. View at Publisher · View at Google Scholar
  2. S. J. Winawer, A. G. Zauber, M. N. Ho et al., “Prevention of colorectal cancer by colonoscopic polypectomy. The national polyp study workgroup,” New England Journal of Medicine, vol. 329, no. 27, pp. 1977–1981, 1993. View at Publisher · View at Google Scholar · View at Scopus
  3. J. D. Hardcastle, J. O. Chamberlain, M. H. Robinson et al., “Randomised controlled trial of faecal-occult-blood screening for colorectal cancer,” The Lancet, vol. 348, no. 9040, pp. 1472–1477, 1996. View at Publisher · View at Google Scholar · View at Scopus
  4. O. Kronborg, C. Fenger, J. Olsen, O. D. Jørgensen, and O. Søndergaard, “Randomised study of screening for colorectal cancer with faecal-occult-blood test,” The Lancet, vol. 348, no. 9040, pp. 1467–1471, 1996. View at Publisher · View at Google Scholar · View at Scopus
  5. J. V. Selby, G. D. Friedman, C. P. Quesenberry Jr., and N. S. Weiss, “A case-control study of screening sigmoidoscopy and mortality from colorectal cancer,” New England Journal of Medicine, vol. 326, no. 10, pp. 653–657, 1992. View at Google Scholar · View at Scopus
  6. P. A. Newcomb, R. G. Norfleet, B. E. Storer, T. S. Surawicz, and P. M. Marcus, “Screening sigmoidoscopy and colorectal cancer mortality,” Journal of the National Cancer Institute, vol. 84, no. 20, pp. 1572–1575, 1992. View at Google Scholar · View at Scopus
  7. S. H. Itzkowitz, L. Jandorf, R. Brand et al., “Improved fecal DNA test for colorectal cancer screening,” Clinical Gastroenterology and Hepatology, vol. 5, no. 1, pp. 111–117, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. G. Castiglione, M. Zappa, G. Grazzini et al., “Screening for colorectal cancer by faecal occult blood test: comparison of immunochemical tests,” Journal of Medical Screening, vol. 7, no. 1, pp. 35–37, 2000. View at Publisher · View at Google Scholar · View at Scopus
  9. T. Morikawa, J. Kato, Y. Yamaji, R. Wada, T. Mitsushima, and Y. Shiratori, “A comparison of the immunochemical fecal occult blood test and total colonoscopy in the asymptomatic population,” Gastroenterology, vol. 129, no. 2, pp. 422–428, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. L. G. van Rossum, A. F. van Rijn, R. J. Laheij et al., “Random comparison of guaiac and immunochemical fecal occult blood tests for colorectal cancer in a screening population,” Gastroenterology, vol. 135, no. 1, pp. 82–90, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. D. A. Lieberman and D. G. Weiss, “One-time screening for colorectal cancer with combined fecal occult-blood testing and examination of the distal colon,” New England Journal of Medicine, vol. 345, no. 8, pp. 555–560, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. J. J. Sung, F. K. Chan, W. K. Leung et al., “Screening for colorectal cancer in chinese: comparison of fecal occult blood test, flexible sigmoidoscopy, and colonoscopy,” Gastroenterology, vol. 124, no. 3, pp. 608–614, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. T. F. Imperiale, D. F. Ransohoff, S. H. Itzkowitz, B. A. Turnbull, and M. E. Ross, “Fecal DNA versus fecal occult blood for colorectal-cancer screening in an average-risk population,” New England Journal of Medicine, vol. 351, no. 26, pp. 2704–2714, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. D. B. Nelson, K. R. McQuaid, J. H. Bond, D. A. Lieberman, D. G. Weiss, and T. K. Johnston, “Procedural success and complications of large-scale screening colonoscopy,” Gastrointestinal Endoscopy, vol. 55, no. 3, pp. 307–314, 2002. View at Publisher · View at Google Scholar · View at Scopus
  15. N. Segnan, C. Senore, B. Andreoni et al., “Comparing attendance and detection rate of colonoscopy with sigmoidoscopy and FIT for colorectal cancer screening,” Gastroenterology, vol. 132, no. 7, pp. 2304–2312, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Halligan, D. G. Altman, S. A. Taylor et al., “CT colonography in the detection of colorectal polyps and cancer: systematic review meta-analysis, and proposed minimum data set for study level reporting,” Radiology, vol. 237, no. 3, pp. 893–904, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. P. J. Pickhardt, J. R. Choi, I. Hwang et al., “Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults,” New England Journal of Medicine, vol. 349, no. 23, pp. 2191–2200, 2003. View at Publisher · View at Google Scholar · View at Scopus
  18. C. D. Johnson, M.-H. Chen, A. Y. Toledano et al., “Accuracy of CT colonography for detection of large adenomas and cancers,” New England Journal of Medicine, vol. 359, no. 12, pp. 1207–1217, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. D. H. Kim, P. J. Pickhardt, A. J. Taylor et al., “CT colonography versus colonoscopy for the detection of advanced neoplasia,” New England Journal of Medicine, vol. 357, no. 14, pp. 1403–1412, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. D. Burling, S. Halligan, A. Slater, M. J. Noakes, and S. A. Taylor, “Potentially serious adverse events at CT colonography in symptomatic patients: National survey of the United Kingdom,” Radiology, vol. 239, no. 2, pp. 464–471, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. M. Zorzi, F. Falcini, C. Fedato et al., “Screening for colorectal cancer in Italy: 2006 survey,” Epidemiologia & Prevenzione, vol. 32, supplement 1, no. 2, pp. 55–68, 2008. View at Google Scholar · View at Scopus
  22. G. Grazzini, G. Castiglione, C. Ciabattoni et al., “Colorectal cancer screening programme by faecal occult blood test in tuscany: first round results,” European Journal of Cancer Prevention, vol. 13, no. 1, pp. 19–26, 2004. View at Publisher · View at Google Scholar · View at Scopus
  23. N. K. Osborn and D. A. Ahlquist, “Stool screening for colorectal cancer: molecular approaches,” Gastroenterology, vol. 128, no. 1, pp. 192–206, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. A. Loktionov, “Cell exfoliation in the human colon: myth, reality and implications for colorectal cancer screening,” International Journal of Cancer, vol. 120, no. 11, pp. 2281–2289, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. C. H. Klaassen, M. A. Jeunink, C. F. M. Prinsen et al., “Quantification of human DNA in feces as a diagnostic test for the presence of colorectal cancer,” Clinical Chemistry, vol. 49, no. 7, pp. 1185–1187, 2003. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Matsushita, Y. Matsumura, Y. Moriya et al., “A new method for isolating colonocytes from naturally evacuated feces and its clinical application to colorectal cancer diagnosis,” Gastroenterology, vol. 129, no. 6, pp. 1918–1927, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. D. Calistri, C. Rengucci, A. C. Gardini et al., “Fecal DNA for noninvasive diagnosis of colorectal cancer in immunochemical fecal occult blood test-positive individuals,” Cancer Epidemiology Biomarkers and Prevention, vol. 19, no. 10, pp. 2647–2654, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Rengucci, P. Maiolo, L. Saragoni, W. Zoli, D. Amadori, and D. Calistri, “Multiple detection of genetic alterations in tumors and stool,” Clinical Cancer Research, vol. 7, no. 3, pp. 590–593, 2001. View at Google Scholar · View at Scopus
  29. D. Calistri, C. Rengucci, C. Molinari et al., “Quantitative fluorescence determination of long-fragment DNA in stool as a marker for the early detection of colorectal cancer,” Cellular Oncology, vol. 31, no. 1, pp. 11–17, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. K. A. Boynton, I. C. Summerhayes, D. A. Ahlquist, and A. P. Shuber, “DNA integrity as a potential marker for stool-based detection of colorectal cancer,” Clinical Chemistry, vol. 49, no. 7, pp. 1058–1065, 2003. View at Publisher · View at Google Scholar · View at Scopus
  31. W. S. Samowitz, M. L. Slattery, J. D. Potter, and M. F. Leppert, “BAT-26 and BAT-40 instability in colorectal adenomas and carcinomas and germline polymorphisms,” American Journal of Pathology, vol. 154, no. 6, pp. 1637–1641, 1999. View at Google Scholar · View at Scopus
  32. O. Buhard, F. Cattaneo, F. W. Yick et al., “Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors,” Journal of Clinical Oncology, vol. 24, no. 2, pp. 241–251, 2006. View at Publisher · View at Google Scholar · View at Scopus
  33. J. Olson, D. H. Whitney, K. Durkee, and A. P. Shuber, “DNA stabilization is critical for maximizing performance of fecal DNA-based colorectal cancer tests,” Diagnostic Molecular Pathology, vol. 14, no. 3, pp. 183–191, 2005. View at Publisher · View at Google Scholar · View at Scopus
  34. J. M. Nechvatal, J. L. Ram, M. D. Basson et al., “Fecal collection, ambient preservation, and DNA extraction for PCR amplification of bacterial and human markers from human feces,” Journal of Microbiological Methods, vol. 72, no. 2, pp. 124–132, 2008. View at Publisher · View at Google Scholar · View at Scopus
  35. R. Deuter, S. Pietsch, S. Hertel, and O. Muller, “A method for preparation of fecal DNA suitable for PCR,” Nucleic Acids Research, vol. 23, no. 18, pp. 3800–3801, 1995. View at Google Scholar · View at Scopus
  36. S. Onouchi, H. Matsushita, S. Nomura, T. Minowa, and Y. Matsumura, “PCR-based assessment of the recovery rate of exfoliated colonocytes or cancer cells from fecal samples depends on the storage conditions after defecation,” Journal of Gastrointestinal and Liver Diseases, vol. 16, no. 4, pp. 369–372, 2007. View at Google Scholar · View at Scopus
  37. H. Zou, J. J. Harrington, K. K. Klatt, and D. A. Ahlquist, “A sensitive method to quantify human long DNA in stool: relevance to colorectal cancer screening,” Cancer Epidemiology Biomarkers and Prevention, vol. 15, no. 6, pp. 1115–1119, 2006. View at Publisher · View at Google Scholar · View at Scopus
  38. T. F. Jones, S. N. Bulens, S. Gettner et al., “Use of stool collection kits delivered to patients can improve confirmation of etiology in foodborne disease outbreaks,” Clinical Infectious Diseases, vol. 39, no. 10, pp. 1454–1459, 2004. View at Publisher · View at Google Scholar · View at Scopus
  39. B. Levin, “Molecular screening testing for colorectal cancer,” Clinical Cancer Research, vol. 12, no. 17, pp. 5014–5017, 2006. View at Publisher · View at Google Scholar · View at Scopus
  40. G. P. Young and P. Rozen, “Fecal immunochemical tests for haemoglobin (FITs): a paradigm shift in non-invasive fecal screening tests for colorectal cancer,” World Gastroenterology News, no. 2, 2006. View at Google Scholar