Validation of Microcirculatory Parameters Derived from the Standard Two-Compartment Model with Murine Xenografts Model

Figure 3

Fractional intravascular space volume of a mouse with HCC xenograft as derived by (a) the standard two-compartment model and (b) by the CD34 staining as shown in the inset of the whole tumor. The blood vessels are outlined in light green in (c) the hotspot. Fractional interstitial space volume of a mouse with HCC xenograft as derived by (d) the standard two-compartment model and (e) by the Masson trichrome staining as shown in the inset of the whole tumor. The interstitial space are outlined in light green in (f) the hotspot.