Liposomal Tumor Targeting in Drug Delivery Utilizing MMP-2- and MMP-9-Binding Ligands
Figure 7
Comparison of doxorubicin concentrations in tumors after a single i.v. injection of CTT2-SL liposome or Caelyx. A2780 xenografts () were collected at 2, 6, 24, 48, 72, and 96 hours after CTT2-liposome or Caelyx injection, and their doxorubicin content was measured using spectrophotometry. Results are shown as μg drug per gram of dry tissue. All values are expressed as the mean ± SD. The differences in each time point are near significant. The overall difference in the AUC is significant.
