Journal of Drug Delivery / 2011 / Article / Fig 5

Research Article

Effects of Selected Anionic β-Cyclodextrins on Persistence of Blood Glucose Lowering by Insulin Glargine after Subcutaneous Injection to Rats

Figure 5

Effects of Sul-β-CyD and SBE7-β-CyD (10 mM) on dissolution from isoelectric precipitation of insulin glargine in phosphate buffer (pH 9.5, I = 0.2) at 25°C. The initial concentration of insulin glargine was 0.1 mM and then precipitated in phosphate buffer (pH 7.4). Each point represents the mean ± S.E.M. of 3 experiments. * , compared to insulin glargine. # , compared to Sul-β-CyD.

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