Journal of Drug Delivery / 2011 / Article / Fig 3

Research Article

Antibody-Hapten Recognition at the Surface of Functionalized Liposomes Studied by SPR: Steric Hindrance of Pegylated Phospholipids in Stealth Liposomes Prepared for Targeted Radionuclide Delivery

Figure 3

Formation of tethered planar bilayers on DMPE-functionalized CM5 chip with liposomes of different lipid compositions. A DMPE-coated chip was treated with liposomes prepared with 4 different lipid compositions: (a) DSPC-containing lipid vesicles that spread and formed a 900 RU tethered planar bilayer, (b) DSPC/DSPE-DTPA-indium-containing lipid vesicles that spread and formed a 1100 RU tethered planar bilayer, and (c) DSPC/DSPE-DTPA-indium/DSPE-PEG-containing lipid vesicles that were unable to spread on the hydrophobic DMPE monolayer.