Research Article
Modeling Drug-Carrier Interaction in the Drug Release from Nanocarriers
Table 4
Properties of the model parameters for Figure
3(a).
| Variables | Parameter | Parameter estimationa | Bootstrap results | F-statistic (P value) | mean | SDb | P value |
| 1 mol% PEG | | 0.4941 | 0.5592 | 0.007 | <1.0 | 164.1721 (P < 0.001) | | 0.0136 | 0.0169 | 3.00E-04 | <1.0 | | 0.0172 | 0.0252 | 8.00E-04 | <1.0 | | –0.9676 | –1.2145 | 0.0263 | <1.0 |
| 3 mol% PEG | | 1.568 | 1.4275 | 0.0182 | <1.0 | 349.7894 (P < 0.001) | | 0.0261 | 0.0277 | 4.00E-04 | <1.0 | | 0.0213 | 0.0228 | 5.00E-04 | <1.0 | | 0.8283 | 0.9656 | 0.0219 | <1.0 |
| 4 mol% PEG | | 1.2728 | 1.2165 | 0.0107 | <1.0 | 470.3850 (P < 0.001) | | 0.039 | 0.0418 | 5.00E-04 | <1.0 | | 0.023 | 0.0252 | 5.00E-04 | <1.0 | | 2.1781 | 2.2303 | 0.0218 | <1.0 |
| 10 mol% PEG | | 2.7849 | 2.4222 | 0.0275 | <1.0 | 782.3148 (P < 0.0001) | | 0.0891 | 0.0841 | 7.00E-04 | <1.0 | | 0.028 | 0.0255 | 3.00E-04 | <1.0 | | 4.7684 | 5.0285 | 0.0251 | <1.0 |
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aParameters are determined using Matlab codes as detailed in Section 3.1.
bSD: standard deviation.
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