Research Article
Modeling Drug-Carrier Interaction in the Drug Release from Nanocarriers
Table 5
Properties of the model parameters for Figure
4(d).
| Variables | Parameter | Parameter estimationa | Bootstrap results | F-statistic (P value) | mean | SDb | P value |
| PLGA50/50 | | 0.1972 | 0.2035 | 0.001 | <1.0 | 16.8532 (P < 0.004) | | 0.0199 | 0.0203 | 1.00E-04 | <1.0 | | 0.03 | 0.0314 | 2.00E-04 | <1.0 | | −1.6872 | −1.7692 | 0.0152 | <1.0 |
| PLGA65/35 | | 0.1633 | 0.1668 | 0.0032 | <1.0 | 8.4857 (P < 0.01) | | 0.0044 | 0.0044 | 1.00E-04 | <1.0 | | 0.0079 | 0.008 | 2.00E-04 | <1.0 | | −2.3984 | −2.4088 | 0.01 | <1.0 |
| PLGA85/15 | | 0.1795 | 0.1854 | 0.0038 | <1.0 | 174.3171 (P < 0.001) | | 0.0068 | 0.0068 | 1.00E-04 | <1.0 | | 0.0176 | 0.0181 | 4.00E-04 | <1.0 | | −3.9408 | −3.9607 | 0.0151 | <1.0 |
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aParameters are determined using a Matlab code as detailed in Section 3.1.
bSD: standard deviation.
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