Modeling the Release Kinetics of Poorly Water-Soluble Drug Molecules from Liposomal Nanocarriers

Figure 3

Transfer of a drug molecule (black bullets) upon the collision of two liposomes (here assumed to be two donor liposomes). The drug distribution function changes from initially 𝑑₁=1, 𝑑₂=0, 𝑑₃=0, 𝑑₄=0, 𝑑₅=1 to 𝑑₁=0, 𝑑₂=1, 𝑑₃=0, 𝑑₄=1, 𝑑₅=0. This represents an example (for 𝑖=5 and 𝑗=1) of the general scheme 𝑑_𝑖→𝑑_𝑖−1, 𝑑_𝑖−1→𝑑_𝑖−1+1, 𝑑_𝑗→𝑑_𝑗−1, and 𝑑_𝑗+1→𝑑_𝑗+1+1.