Research Article

Preparation and Characterization of Stealth Archaeosomes Based on a Synthetic PEGylated Archaeal Tetraether Lipid

Table 1

Size (cumulant results), polydispersity (Ip), and zeta potential of prepared formulations. (ND = nondetermined).

FormulationSize (nm), (Std Dev)IpZeta potential (mV)

Egg-PC/PEG45-DSPE70 (40)0.30−20.0 ± 9
Egg-PC/PEG45-Tetraether80 (30)0.26−13.0 ± 6
CF-encapsulated Egg-PC/PEG45-DSPE90 (37)0.21Nd
CF-encapsulated Egg-PC/PEG45-Tetraether100 (45)0.26Nd