A Novel Domperidone Hydrogel: Preparation, Characterization, Pharmacokinetic, and Pharmacodynamic Properties

Table 1

Solubility of domperidone in buffer solutions and distilled water (mean ± SD, 𝑛=3). The drug concentration (μg/mL) represents its solubility.

pH	Raw domperidone	Domperidone dispersion
1.0	566.8 ± 50.9	36211.8 ± 1.3
5.0	243.3 ± 4.2	3198.4 ± 21.7
7.0	2.9 ± 0.33	10.6 ± 0.27
Distilled water	4.5 ± 0.3	205.5 ± 3.7