Journal of Drug Delivery / 2011 / Article / Tab 2

Review Article

Enhanced Transport Capabilities via Nanotechnologies: Impacting Bioefficacy, Controlled Release Strategies, and Novel Chaperones

Table 2

List of various “bottom up” processes and influence on particle properties.

Bottom up processesProperties controlled

Crystallization(i) Size, shape
(ii) Crystalline structure—Crystalline/amorphous
(iii) Polymorph

Precipitation(i) Size, shape
(ii) Surface area

Encapsulation in polymers(i) Size, shape
(ii) API concentration
(iii) Particle nanostructure

Chemical reactions(i) Size, shape
(ii) Purity
(iii) Surface area

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