Journal of Drug Delivery / 2011 / Article / Tab 2

Research Article

Optimization of Liposomal Lipid Composition for a New, Reactive Sulfur Donor, and In Vivo Efficacy Studies on Mice to Antagonize Cyanide Intoxication

Table 2

Rh-load optimization with and without DOTAP.

Composition of liposomesOriginal Rh concentration (mg/mL)% of Rh incorporation determined by Bradford

POPC : Chol : PEG-PE-2000 = 56.9 : 38: 5.11.0016.6
POPC : Chol : PEG-PE-2000 = 56.9 : 38: 5.10.2526.9
POPC : Chol : PEG-PE-2000 : DOTAP = 82.7 : 9.2 : 5.1 : 3.01.6718.2
POPC : Chol : PEG-PE-2000 : DOTAP = 82.7 : 9.2 : 5.1 : 3.00.5055.8
POPC : Chol : PEG-PE-2000 : DOTAP = 82.7 : 9.2 : 5.1 : 3.00.2574.0
POPC : Chol : PEG-PE-2000 : DOTAP = 82.7 : 9.2 : 5.1 : 3.01.0052.9

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