Journal of Drug Delivery / 2011 / Article / Tab 3

Research Article

Optimization of Liposomal Lipid Composition for a New, Reactive Sulfur Donor, and In Vivo Efficacy Studies on Mice to Antagonize Cyanide Intoxication

Table 3

Encapsulation efficiencies for DTO in various liposome compositions with and without DOTAP. DTO concentration was 2.0 mM. Total lipid concentration was 10.0 mg/mL.

Liposomal composition (mol%)Encapsulation efficiency (%) with various lipid components
LipidCholPEG-PE-2000DOTAPPOPCDOPCLEC

82.719.195.13.078.4 ± 2.381.7 ± 3.164.3 ± 3.0
85.419.495.160.7 ± 3.063.8 ± 1.261.6 ± 1.5

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