Optimization of Liposomal Lipid Composition for a New, Reactive Sulfur Donor, and In Vivo Efficacy Studies on Mice to Antagonize Cyanide Intoxication

Table 5

Relative prophylactic antidotal potency ratios (RAPRs) to express enhancing effects by Rh, SN, and coencapsulated TS.

Enhancing effects by Rh	RAPR
Comparison of exps 5 and 2	3.9/2.2 = 1.8
Comparison of exps 7 and 4	15.3/6.7 = 2.3
Enhancing effects by SN	RAPR
Comparison of exps 4 and 3	6.7/4.8 = 1.4
Comparison of exps 7 and 6	15.3/4.9 = 3.1
Enhancement by coencapsulated TS	RAPR
Comparison of exps 3 and 2	4.8/2.2 = 2.1
Comparison of exps 6 and 5	4.9/3.9 = 1.3