In vivo targeting and imaging using QDs. (a) Ex vivo tissue examination of QD-labeled cancer cells trapped in a mouse lung [129]. (b) Near-infrared fluorescence of water-soluble type II QDs taken up by sentinel lymph nodes [130]. (c) In vivo simultaneous imaging of multicolor QD-encoded microbeads injected into a live mouse [131]. (d) Molecular targeting and in vivo imaging of a prostate tumor in a mouse using a QD-antibody conjugate (red) [131]. Reprinted from Gao et al. [128], with the permission of Elsevier.
