Nanoprodrugs of NSAIDs: Preparation and Characterization of Flufenamic Acid Nanoprodrugs

Figure 8

Cellular uptake of fluorescent-labeled nanoprodrugs in U87 glioma cells. Cells were incubated with FA-TEG-ALA nanoprodrug ((a)–(c)), FA₂TEG nanoprodrug ((d)–(f)) and in dye-treated medium as control ((g)–(i)). Left and middle panels show images of overlapped fluorescence of DAPI and coumarin 6, left with lower and middle with higher magnification. Right panel shows images of fluorescence of coumarin 6 only.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)