Review Article
Cyclodextrin-Containing Polymers: Versatile Platforms of Drug Delivery Materials
Table 5
Selected physicochemical properties of siRNA-containing, RONDEL-based nanoparticles.
| | Property | Method | Result |
| | Size (diameter) | Dynamic light scattering | 60 to 150 nm | | Zeta potential (surface charge) | Electrophoretic mobility | 0 to mV | | Nanoparticle molar mass | Multiangle laser light scattering (MALS) | ~7e7 to ~1e9 g/mol | | Stoichiometry (of 70 nm nanoparticle) | Various, including MALS | CAL101: ~10,000 molecules/particle | | AD-PEG: ~4,000 molecules/particle | | AD-PEG-Tf: ~100 molecules/particle | | siRNA: ~2,000 molecules/particle |
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