Composite Polylactic-Methacrylic Acid Copolymer Nanoparticles for the Delivery of Methotrexate
Figure 15
Energy-minimized geometrical preferences of the MTX-PLA-MAA complexes derived from molecular mechanics computations: (a) MAA-MTX, (b) PLA-MTX, and (c) depiction of adsorption of MTX on MAA nanoparticle (brown colored-tube rendered). MTX is rendered in spheres, and polymers are in ball/cylinder rendering. Color codes for elements are C (cyan), N (blue), O (red), and H (white).
