Journal of Drug Delivery / 2012 / Article / Fig 1

Review Article

Lipoplatin Formulation Review Article

Figure 1

Depiction of a lipoplatin nanoparticle (b). Cisplatin molecules are depicted as blue spheres surrounded by the lipid bilayer with the PEGylated lipid sticking out like hair from the outer surface. Thus, this toxic substance, cisplatin, is camouflaged by its lipid shell as a nutrient. This nanoparticle can pass undetected by macrophages after intravenous injection to human cancer patients because of its PEG coating thus escaping immune surveillance [20]. © CNRS Photothèque/SAGASCIENCE/CAILLAUD François.