Review Article
Lipoplatin Formulation Review Article
Table 3
Toxicity/statistical differences.
| Toxicity grade 1–4 | Arm A | Arm B | | n (%) | n (%) | P value* |
| Anemia | 50 (43.9) | 62 (54.9) | 0.112 | Leucopenia (neutropenia) | 38 (33.3) | 52 (45.2) | 0.017 | Thrombocytopenia | 2 (1.8) | 3 (2.6) | 1.000† | Nephrotoxicity (renal) | 7 (6.1) | 46 (40.0) | <0.001 | Neurotoxicity | 52 (45.6) | 63 (54.8) | 0.145 | GI toxic nausea/vomiting | 37 (32.5) | 52 (45.2) | 0.042 | GI diarrhea | 2 (1.8) | 3 (2.6) | 1.000† | Asthenia | 65 (57.0) | 82 (71.3) | 0.019 | Alopecia | 96 (84.2) | 87 (75.7) | 0.134 |
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GI, gastrointestinal.
*Pearson’s chi-square test. †Fisher’s exact test.
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