Table 3: Excipients which can be used in an ophthalmic emulsion.

FunctionExcipients

Osmotic agentsMannitol, glycerol, sorbitol, propylene glycol, dextrose

OilsMedium chain triglycerides, mineral oil, vegetal oil such a castor oil

Cationic agentsBenzalkonium chloride, cetylpyridinium chloride, cetrimide, benzethonium chloride

SurfactantsPolysorbates, cremophors, poloxamers, tyloxapol, vitamin E-TPGS

Buffers, salts, and anionsTo be avoided if possible

WaterWater for injections

OthersViscosifying agents: preferably neutral Preservatives: preferably nonionic and hydrophilic