Cosmetotextiles with Gallic Acid: Skin Reservoir Effect

Table 4

In vitro percutaneous absorption of GA (gallic acid) in Lip and MM formulations and the PA and CO cosmetotextiles.

(a)

GA in formulations	GA in Lip		GA in MM
Compartments	%	µg/cm²	%	µg/cm²
Total applied	—	76.34	—	79.03
Wash/fabric	83.97±0.40	55.08±1.40	87.61±1.87	59.38±2.33
SC	6.78±0.69	4.46±0.55	4.41±0.28	2.98±0.14
E	1.37±0.14	0.90±0.07	1.14±0.25	0.77±0.15
D	1.20±0.09	0.78±0.04	1.07±0.10	0.73±0.05
R. F	6.68±0.65	4.38±0.36	5.77±1.25	3.90±0.77
Perc. Abs (E + D + RF)	9.25±0.86	6.06±0.48	7.98±1.60	5.40±0.9
Recovery		65.59±1.65		67.76±1.23

(b)

GA in CO	GA in Lip on CO		GA in MM on CO
Compartments	%	µg/cm²	%	µg/cm²
Total applied	—	147.95	—	242.61
Wash/fabric	91.84±9.72	131.28±14.38	87.34±6.30	210.85±15.68
SC	5.60±1.42	8.60±2.26	5.24±1.02	12.64±2.48
E	1.81±0.87	2.78±1.93	1.84±0.35	4.45±0.86
D	0.75±0.41	1.15±0.66	0.87±0.54	2.12±1.30
R. F	0.00±0.00	0.00±0.00	4.72±0.44	16.10±1.03
Perc. Abs (E + D + RF)	2.56±0.92	3.93±1.99	7.43±0.51	22.67±1.22
Recovery	—	143.81±4.25	—	241.47±11.69

(c)

GA in PA	GA in Lip on PA		GA in MM on PA
Compartments	%	µg/cm²	%	µg/cm²
Total applied	—	395.90	—	479.59
Wash/fabric	96.64±5.56	403.30±22.02	97.20±6.21	464.15±29.78
SC	2.51±0.81	10.49±3.21	2.52±0.33	12.05±1.57
E	0.66±0.44	2.78±1.76	0.22±0.02	1.05±0.08
D	0.33±0.04	1.39±0.16	0.06±0.10	0.28±0.49
R. F	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00
Perc. Abs (E + D + RF)	0.99±0.55	4.17±1.85	0.28±0.03	1.33±0.09
Recovery	—	417.75±31.87	—	477.53±27.71

SC: stratum corneum, E: epidermis, D: dermis, and R.F: receptor fluid.