Development of Dorzolamide Loaded 6-O-Carboxymethyl Chitosan Nanoparticles for Open Angle Glaucoma

Table 1

Effect of solvent ratios on yield of OCM-CS.

Serial number	Samples	H2O/IPA	Yield (%)
1	OCM-CS-1	1/9	75.39±1.15
2	OCM-CS-2	0/10	48.62±0.89
3	OCM-CS-3	2/8 (1/4)	89.13±2.14
4	OCM-CS-4	5/5 (1/1)	78.54±1.53
5	OCM-CS-5	8/2 (4/1)	16.29±0.92
6	OCM-CS-6	10/0	5.68±0.45

Values are expressed as mean ± standard deviation, 𝑛=3.
OCM-CS: 6-𝑂-carboxymethyl chitosan; IPA: isopropyl alcohol; H₂O: water.