Research Article
Mucoadhesive Hydrogel Films of Econazole Nitrate: Formulation and Optimization Using Factorial Design
Table 8
Diameter of zone of inhibition of optimized MHF.
| Time (hr) | 0 | 1 | 2 | 3 | 4 | 6 | 8 | 10 | 12 |
| Diameter of zone of inhibition* (mm) | 0 | 2.11 ± 0.56 | 3.24 ± 0.56 | 4.21 ± 0.24 | 5.44 ± 0.09 | 8.24 ± 0.79 | 11.39 ± 0.70 | 14.16 ± 0.82 | 16.57 ± 0.59 | Corresponding percent drug release* | 0 | 9.63 ± 0.89 | 14.79 ± 0.81 | 19.22 ± 0.33 | 24.84 ± 0.19 | 37.62 ± 1.08 | 52.00 ± 0.99 | 64.65 ± 1.14 | 75.65 ± 0.67 |
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