Design Optimization and In Vitro-In Vivo Evaluation of Orally Dissolving Strips of Clobazam

Table 10

Comparison of pharmacokinetic parameters following administration of 5 mg clobazam in orodispersible film (F6) and frisium tablets to six rabbits ().

Parameters	Orodispersible film (mean ± SD); (test)	Frisium (mean ± SD) (reference)	Test/reference ratio
(ng/mL)			95.87
(ng hmL^−1)			98.125
(ng hmL^−1)			99.213
(h)			71.428
(h)			93.987