Design Optimization and In Vitro-In Vivo Evaluation of Orally Dissolving Strips of Clobazam

Table 5

Release kinetic study of orally dissolving strips of clobazam using different kinetic models.

Formulation code	Kinetic models
	Zero order	First order	Higuchi	Korsmeyer	Best fit kinetic
	F1	0.947	0.826	0.971		0.967	Higuchi
F2	0.924	0.961	0.996	0.984	Higuchi
F3	0.978	0.984	0.997	0.986	Higuchi
F4	0.965	0.950	0.989	0.952	Higuchi
F5	0.985	0.952	0.994	0.992	Higuchi
F6	0.952	0.861	0.998	0.993	Higuchi
F7	0.702	0.703	0.987	0.929	Higuchi
F8	0.959	0.933	0.996	0.980	Higuchi
F9	0.848	0.881	0.988	0.980	Higuchi