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Journal of Drug Delivery
Volume 2014 (2014), Article ID 583612, 11 pages
Review Article

Interpenetrating Polymer Networks as Innovative Drug Delivery Systems

School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh 244102, India

Received 10 January 2014; Accepted 27 March 2014; Published 14 May 2014

Academic Editor: Sven Frøkjær

Copyright © 2014 Alka Lohani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Polymers have always been valuable excipients in conventional dosage forms, also have shown excellent performance into the parenteral arena, and are now capable of offering advanced and sophisticated functions such as controlled drug release and drug targeting. Advances in polymer science have led to the development of several novel drug delivery systems. Interpenetrating polymer networks (IPNs) have shown superior performances over the conventional individual polymers and, consequently, the ranges of applications have grown rapidly for such class of materials. The advanced properties of IPNs like swelling capacity, stability, biocompatibility, nontoxicity and biodegradability have attracted considerable attention in pharmaceutical field especially in delivering bioactive molecules to the target site. In the past few years various research reports on the IPN based delivery systems showed that these carriers have emerged as a novel carrier in controlled drug delivery. The present review encompasses IPNs, their types, method of synthesis, factors which affects the morphology of IPNs, extensively studied IPN based drug delivery systems, and some natural polymers widely used for IPNs.