Interpenetrating Polymer Networks as Innovative Drug Delivery Systems

Table 1

Delivery of variety of drugs via different IPN based novel carriers.

Drug	Therapeutic category	Carrier system	Inference	Reference
5-Fluorouracil and diclofenac sodium	Antimetabolite and anti-inflammatory	Hydrogels	Localized drug delivery	[14]
Buflomedil hydrochloride		Microspheres	Controlled oral delivery of highly water soluble drug	[15]
5-Fluorouracil	Antimetabolite	Hydrogels	pH sensitivity to localize drug delivery	[16]
Diclofenac sodium	Anti-inflammatory	Microbead	Intestine specific drug release with minimum gastric side effects of drug	[17]
Aspirin	Anti-inflammatory	Microparticles	Intestinal specific drug delivery	[18]
Chlorpheniramine maleate	Antihistaminics	Beads	Controlled drug delivery	[19]
Ofloxacin hydrochloride	Antibacterial	Beads	Sustained drug release	[20]
Simvastatin	Hypolipidemic	IPN beads	Controlled drug release	[21]
Clarithromycin	Anti-Helicobacter pylori	Hydrogels	Stomach-specific drug delivery	[22]
Cloxacillin	Antibiotic	Floating beads	Prolonged sustained release in simulated gastric fluid	[23]
Bovine serum albumin	Serum albumin	Hydrogel beads	Improved drug release in physiological saline solution	[24]
Insulin	Hypoglycaemic	Microparticles	Innovative carrier for oral insulin delivery	[25]
Cefadroxil	Antimicrobial	Microgels	pH dependent extended drug release	[26]
Metformin hydrochloride	Hypoglycaemic	Mucoadhesive; microspheres	Prolonged gastric residence with sustained release	[27]
Prazosin hydrochloride	Antihypertensive	Hydrogel	Extended drug release through transdermal route	[28]
Ciprofloxacin hydrochloride	Antibacterial	IPN scaffold	For quick and regulated wound healing	[29]