Research Article
Development of Risperidone PLGA Microspheres
Table 1
Properties of Risperidone PLGA microspheres.
| | Formulation | A | B
| C | D |
| | MW | 45 kDa | 74 kDa | 54 kDa | 65 kDa | | PLGA type | 50 : 50 | 50 : 50 | 75 : 25 | 75 : 25 | | Drug load (%) | 25 | 34 | 34 | 33 | | Bulk density (g/cc) | 0.76 | 0.67 | 0.65 | 0.68 | | Mean particle size (μm) | 24.6 | 18.9 | 17.1 | 21.9 | | Dose of Risperidone (mg/kg) | 20 | 20 | 40 | 40 |
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